Karin's chakra being consumed, healing the target. These traits are strong enough to survive the removal of tailed beasts, although they are still left severely weakened afterwards. This also enables them to survive and endure much more severe injuries while likewise able to recover from injuries and exhaustion with much greater efficiency in short periods of time. As such, they have very long lifespans and likewise age slower Mito Uzumaki was born before the founding of Konoha yet lived well into the reign of the Third Hokage while still retaining full-colouring in her hair. Uzumaki naturally possess incredibly strong life-forces. The typical appearance of an Uzumaki fūinjutsu. At some point, the clan was recognised as being part of Konoha, with its only known member, Naruto, marrying a Hyūga clansmen and having two children. After his parents' deaths, Naruto was given his mother's surname, Uzumaki, by the Third Hokage to protect him from his father's enemies. Of the known members, Nagato was raised in the outskirts of Amegakure, Karin apparently lived in Kusagakure for a time, Kushina in Konoha, who had a son, Naruto. The survivors of Uzushio's destruction went into hiding and spread throughout the world. At some point after Kushina Uzumaki immigrated to Konoha, some of the world's nations banded together to destroy Uzushiogakure, believing the village was too powerful to be allowed to continue. The Uzumaki's skill with fūinjutsu earned them both respect and fear throughout the ninja world. In time, the Uzumaki Clan's Mask Storage Temple was even constructed on Konoha's outskirts.

Konoha and the Uzumaki's own Uzushiogakure remained close allies over the following decades, with the Uzumaki providing fūinjutsu (among other things) to Konoha whenever there was a need. Following the founding of Konohagakure at the end of the Warring States Period, the Senju chose to symbolise their clans' friendship by adding the Uzumaki's emblem to Konoha's flak jackets.

Through the years, the Uzumaki and Senju kept close ties, with members at times marrying between clans, as with Hashirama Senju and Mito Uzumaki. The Uzumaki, being descendants of Asura Ōtsutsuki, also shared distant blood relation with the Senju clan. The Uzumaki and Senju after the creation of their villages. Despite the fall of Uzushiogakure and decline of the clan, it never quite went extinct as most of its known members have since resided in Konohagakure the clan itself was recognised as active against 15 years after the Fourth Shinobi World War. Its members are renown for having bright, red hair, possessing incredibly strong life-forces and chakra, and their sealing prowess. The Uzumaki Clan ( うずまき一族, Uzumaki Ichizoku) was formerly a prominent clan in Uzushiogakure.

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